AGI-24512, CAS [[2201066-53-5]]

Product Overview

• Article Name: AGI-24512, CAS [[2201066-53-5]]
• Biozol Catalog Number: BYT-ORB1707707
• Supplier Catalog Number: orb1707707
• Alternative Catalog Number: BYT-ORB1707707-1,BYT-ORB1707707-10,BYT-ORB1707707-100,BYT-ORB1707707-200,BYT-ORB1707707-25,BYT-ORB1707707-5,BYT-ORB1707707-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: S-adenosylmethionine Synthetase, PRMT5, HCT116, MAT2A, MATA2, MTAP, methylthioadenosine phosphorylase, Methionine Adenosyltransferase (MAT), anticancer, antiproliferative, AGI 24512, AGI24512, AGI-24512, DNA damage response, DNA

Product Description

AGI-24512 is a potent and selective MAT2A inhibitor (IC50: 8 nM) with antiproliferative effects in MTAP-deficient cancer cells. Its mechanism, which induces DNA damage, supports its use in both in vitro and in vivo studies exploring novel combination therapies for oncology research.

Product Properties

• Molecular Weight: 400.47
• Purity: 98.55% (May vary between batches)
• CAS Number: [2201066-53-5]
• Formula: C24H24N4O2
• Target: DNA,Methionine Adenosyltransferase (MAT)

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.24 mM),DMSO:80 mg/mL (199.77 mM),H2O:< 0.1 mg/mL (insoluble)