ABL127 is a potent, selective, and covalent inhibitor of Protein Methylesterase 1 (PME-1), demonstrating low nanomolar IC50 values of 6.4 nM and 4.2 nM in HEK293T and MDA-MB-231 cells, respectively. This small molecule is a valuable chemical probe for investigating PME-1s role in cancer biology and cellular signaling pathways in vitro.
Molecular Weight:
332.35
CAS Number:
[1073529-41-5]
Formula:
C17H20N2O5
Target:
Phosphatase,Others
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