Abaperidone is a potent dual antagonist of the 5-HT2A (IC50 = 6.2 nM) and dopamine D2 (IC50 = 17 nM) receptors. This research compound exhibits atypical antipsychotic potential, as evidenced by its ability to reduce basal hsp70 mRNA expression in rat striatum and prefrontal cortex in vivo studies.
Molecular Weight:
452.47
Purity:
99.77% (May vary between batches)
CAS Number:
[183849-43-6]
Formula:
C25H25FN2O5
Target:
5-HT Receptor,Dopamine Receptor
Application Notes:
Solubility: DMSO:1.46 mg/mL (3.23 mM)
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