JAK3 Covalent Inhibitor-1 is a potent and selective small molecule inhibitor of Janus kinase 3 (JAK3) with an IC50 of 11 nM, showing 246-fold selectivity over other JAK family members. This compound is a valuable research tool for investigating JAK3-dependent signaling in immunological and inflammatory disease models, both in vitro and in vivo.
Molecular Weight:
448.47
CAS Number:
[2300106-50-5]
Formula:
C22H17FN6O2S
Target:
JAK
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