JAK-IN-1 is a potent, cell-permeable inhibitor of JAK kinases, demonstrating a favorable selectivity profile with IC50 values of 0.26 nM (JAK1), 0.8 nM (JAK2), and 3.2 nM (JAK3). It is a valuable chemical tool for investigating JAK-STAT signaling in cellular and biochemical assays relevant to immunology and oncology research.
Molecular Weight:
380.44
CAS Number:
[1334673-53-8]
Formula:
C20H24N6O2
Target:
JAK,Others
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