human eNOS, GW 274150 phosphate, GW274150 phosphate, GW-274150 Phosphate
GW274150 phosphate is a selective, orally active iNOS inhibitor with an IC50 of 0.2 µM in J774 cells. It demonstrates efficacy in preclinical models, attenuating experimental renal ischemia-reperfusion injury and exhibiting analgesic effects in rat models of inflammatory and neuropathic pain.
Molecular Weight:
317.3
Purity:
98.02% (May vary between batches)
CAS Number:
[438542-15-5]
Formula:
C8H20N3O6PS
Target:
NO Synthase,NOS
Application Notes:
Solubility: H2O:80 mg/mL (252.13 mM)
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