Fiboflapon sodium (GSK2190915) is a potent and orally active inhibitor of 5-lipoxygenase-activating protein (FLAP), exhibiting a 2.9 nM binding affinity and an IC50 of 76 nM for LTB4 inhibition in human whole blood. This FLAP inhibitor is a valuable research tool for investigating leukotriene biosynthesis in inflammatory pathways, applicable in both in vitro and in vivo experimental models.
Molecular Weight:
660.83
CAS Number:
[1196070-26-4]
Formula:
C38H43N3NaO4S
Target:
FLAP,LTR,Leukotriene Receptor
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