GNF362 is a potent, selective, and orally bioavailable inhibitor of inositol trisphosphate 3-kinase B (ITPKB), also inhibiting ITPKA and ITPKC. It has been shown in research to overcome temozolomide chemoresistance, deplete alloreactive T-cells, and reverse ITPKA-driven cell migration in experimental models.
Molecular Weight:
426.44
Purity:
99.63% (May vary between batches)
CAS Number:
[1003019-41-7]
Formula:
C22H21F3N6
Target:
Phosphatase
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