GNE684 is a potent and selective RIP1 kinase inhibitor, demonstrating species-specific binding affinity with apparent Ki values of 21 nM (human), 189 nM (mouse), and 691 nM (rat). This small molecule is a valuable research tool for investigating necroptosis and inflammatory pathways in both cellular and animal models of disease.
Molecular Weight:
432.48
CAS Number:
[2438637-64-8]
Formula:
C23H24N6O3
Target:
RIP kinase,TNF
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