4-Methoxylonchocarpin is a natural compound isolated from Abrus precatorius roots, demonstrating potent anti-inflammatory activity. It functions by inhibiting LPS binding to TLR4 in macrophages, thereby suppressing NF-kappaB-mediated TNF-alpha expression, and has shown efficacy in a murine TNBS-induced colitis model. This makes it a valuable small molecule for researching TLR4/NF-kappaB signaling in inflammatory diseases.
Molecular Weight:
336.38
Purity:
98.67% (May vary between batches)
CAS Number:
[51589-67-4]
Formula:
C21H20O4
Target:
TLR,Interleukin,TNF,NF-kappaB
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