Divarasib, CAS [[2417987-45-0]]

Product Overview

• Article Name: Divarasib, CAS [[2417987-45-0]]
• Biozol Catalog Number: BYT-ORB1737448
• Supplier Catalog Number: orb1737448
• Alternative Catalog Number: BYT-ORB1737448-1, BYT-ORB1737448-1, BYT-ORB1737448-10, BYT-ORB1737448-100, BYT-ORB1737448-25, BYT-ORB1737448-5, BYT-ORB1737448-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Divarasib, KRAS G12C, GDC6036, GDC-6036, GDC 6036

Product Description

Divarasib (GDC-6036) is a potent, selective, and oral KRAS G12C inhibitor with sub-nanomolar IC50, which irreversibly traps the oncoprotein in an inactive state to suppress tumor growth. It is actively researched in vitro and in vivo for treating solid tumors such as non-small cell lung cancer and colorectal cancer.

Product Properties

• Molecular Weight: 622.06
• Purity: 99.96% (May vary between batches)
• CAS Number: [2417987-45-0]
• Formula: C29H32ClF4N7O2
• Target: Ras,Kras

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (5.3 mM),DMSO:90 mg/mL (144.68 mM)