L2-b is a bifunctional small molecule that targets amyloid-beta (Abeta) pathology by chelation of copper and zinc. It inhibits metal-induced Abeta aggregation, disrupts pre-formed aggregates in AD brain homogenates, and reduces associated reactive oxygen species in cellular models, thereby improving neuronal cell viability. This makes it a valuable research tool for studying metallobiology in Alzheimers disease.
Molecular Weight:
227.3
CAS Number:
[52688-60-5]
Formula:
C14H17N3
Target:
Others
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