CBP501 is a G2 checkpoint inhibitor peptide that abrogates the cell cycle arrest by targeting kinases like MAPKAP-K2 and CHK1, which regulate Cdc25C. This inhibition prevents Cdc2/cyclin B activation, blocking mitotic entry. It has been utilized in preclinical cancer research, showing potential to enhance chemotherapy efficacy in both in vitro and in vivo models.
Molecular Weight:
1929.06
CAS Number:
[565434-85-7]
Formula:
C86H122F5N29O17
Target:
CaMK,Others
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