EGFR/HER2-IN-9 is a potent dual inhibitor of EGFR (IC50 = 3.2 nM) and HER2 (IC50 = 14 nM), which also effectively targets the EGFR T790M resistance mutation (IC50 = 8.3 nM). This compound is a valuable research tool for investigating oncogenic signaling in vitro and has shown antitumor efficacy in preclinical cancer models, including non-small cell lung cancer.
Molecular Weight:
513.95
CAS Number:
[1637253-79-2]
Formula:
C25H25ClFN5O4
Target:
Others,EGFR
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