SHP2/HDAC-IN-1 is a potent dual allosteric inhibitor of SHP2 (IC50=20.4 nM) and HDAC1 (IC50=25.3 nM). It demonstrates potential for cancer immunotherapy research by activating T-cells, enhancing antigen presentation, and promoting cytokine secretion in preclinical studies.
Molecular Weight:
660.59
CAS Number:
[2831230-38-5]
Formula:
C34H35Cl2N7O3
Target:
HDAC,Others,Phosphatase
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