RAGE/SERT-IN-1 is a dual-target inhibitor of the receptor for advanced glycation end products (RAGE) and the serotonin transporter (SERT), with IC50 values of 8.26 µM and 31.09 nM, respectively. This orally active compound has demonstrated neuroprotective effects against Abeta-induced toxicity in vitro and alleviates depressive-like behaviors in mouse models, supporting research into Alzheimers disease and depression comorbidity.
Molecular Weight:
637.28
CAS Number:
[2766739-35-7]
Formula:
C38H41ClN4OS
Target:
Others,Serotonin Transporter,Beta Amyloid
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