SARS-CoV-2 Mpro-IN-5 is a dual-target antiviral agent, inhibiting the viral Main Protease (Mpro, IC50=1800 nM) and host Cathepsin L (CatL, IC50=145 nM). It effectively blocks viral replication in cellular models like hACE2-A549 cells (IC50=14.7 nM), making it a valuable chemical probe for studying coronavirus entry and replication mechanisms in vitro.
Molecular Weight:
638.73
Formula:
C34H43FN4O7
Target:
SARS-CoV,Others
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