DBCO-Maleimide, CAS [[1395786-30-7]]

Product Overview

• Article Name: DBCO-Maleimide, CAS [[1395786-30-7]]
• Biozol Catalog Number: BYT-ORB1909431
• Supplier Catalog Number: orb1909431
• Alternative Catalog Number: BYT-ORB1909431-1, BYT-ORB1909431-10, BYT-ORB1909431-100, BYT-ORB1909431-25, BYT-ORB1909431-5, BYT-ORB1909431-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Cleavable, ADCLinker, ADC Linker, DBCO Maleimide, DBCO-MAL, DBCOMaleimide, DBCO-Maleimide

Product Description

DBCO-Maleimide (DBCO-MAL) is a heterobifunctional, non-cleavable linker used in constructing antibody-drug conjugates (ADCs). It enables stable, site-specific conjugation via copper-free click chemistry and maleimide-thiol coupling, facilitating ADC development for both in vitro and in vivo cancer research applications.

Product Properties

• Molecular Weight: 427.45
• Purity: 98.53% (May vary between batches)
• CAS Number: [1395786-30-7]
• Formula: C25H21N3O4
• Target: ADC Linker

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.72 mM),DMSO:80 mg/mL (187.16 mM)