YM158 free base is a potent, dual antagonist of thromboxane A2 (TXA2) and leukotriene D4 (LTD4) receptors, exhibiting high selectivity with pA2 values of approximately 8.81 and 8.87, respectively. This compound is a valuable research tool for investigating the roles of these pro-inflammatory mediators in cardiovascular and pulmonary diseases, applicable in both in vitro and in vivo experimental models.
