2-Amino-6-cyclopropylamino-9H-purine,the key intermediate of abacavir was synthesized from ethyl cyanoacetate by nitrosation,cyclization with guanidine hydrochloride in the presence of EtONa and reduction to give 2,4,5-triamino-6-hydroxypyrimidine.
Molecular Weight:
190.2
Purity:
>98% (HPLC)
CAS Number:
[120503-69-7]
Formula:
C8H10N6
Target:
PD-1/PD-L1
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