DM1-SMe is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines.
Molecular Weight:
784.4
Purity:
>98% (HPLC)
CAS Number:
[138148-68-2]
Formula:
C36H50ClN3O10S2
Target:
Estrogen Receptor/ERR
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