ATIC-IN-1 (compound 14) is an inhibitor targeting the dimerization of Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), with a K i of 685 nM. This dimerization is crucial for the enzymes AICAR transformylase function. Additionally, ATIC-IN-1 exhibits anti-tumor properties by reducing cell proliferation and cell division rates.
Molecular Weight:
463.53
CAS Number:
[1402453-15-9]
Formula:
C21H33N7O5
Target:
Others
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