This small molecule BCRP inhibitor reverses multidrug resistance by blocking BCRP and P-gp efflux pumps. It enhances the cytotoxicity and intracellular accumulation of chemotherapeutics like mitoxantrone and colchicine in resistant cancer cell lines, such as H460/MX20 and KB-C2 cells, in vitro.
Molecular Weight:
339.40
Formula:
C19H13N7
Target:
Others
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