Sulfonadyn-47 is a dynamin GTPase inhibitor with an IC50 of 3.5 µM, disrupting clathrin-mediated endocytosis in cells and synaptic vesicle recycling in synaptosomes. It demonstrates in vivo anticonvulsant efficacy in a 6 Hz corneal kindling mouse seizure model at 30-60 mg/kg, supporting research in neurobiology and endocytosis.
Molecular Weight:
459.40
Formula:
C22H23BrN2O2S
Target:
Others
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