SLU-10482 is a potent antiparasitic small molecule that inhibits Cryptosporidium parvum proliferation in vitro (EC50 = 0.07 µM in HCT-8 cells) and reduces oocyst shedding in infected mice at 5-15 mg/kg BID. Its reduced hERG affinity (Kd = 43 µM) versus SLU-2633 suggests an improved cardiac safety profile for research into cryptosporidiosis therapeutics.
Molecular Weight:
408.35
CAS Number:
[2755451-45-5]
Formula:
C18H16F4N6O
Target:
Parasite,Others
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