AB-680 ammonium is a highly potent and selective inhibitor of human CD73 (ecto-5-nucleotidase), with a Ki of 4.9 pM and >10,000-fold selectivity over CD39. This small molecule is a valuable research tool for investigating adenosine-mediated immunosuppression in oncology, demonstrating anti-tumor efficacy in both cellular assays and in vivo models.
Molecular Weight:
614.89
Formula:
C20H30ClFN6O9P2
Target:
CD73,Others
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