(+)-Mesembrine is a potent and selective aryloctahydroindole alkaloid that acts as a serotonin transporter (SERT) inhibitor (K i = 1.4 nM) and a phosphodiesterase 4B (PDE4B) inhibitor (IC50 = 7.8 µM). This dual activity profile makes it a valuable research tool for neuropharmacological studies, particularly in investigating mood disorders and cognitive function in vitro.
Molecular Weight:
289.37
CAS Number:
[468-53-1]
Formula:
C17H23NO3
Target:
PDE,Others,5-HT Receptor
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