(-)-Sesamin is a neuroprotective lignan studied for Parkinsons disease research. It demonstrates efficacy in models of 6-OHDA-induced neurotoxicity by modulating key signaling pathways, including activation of ERK1/2 and inhibition of p38/JNK-caspase-3 cascades, as shown in both in vitro and in vivo studies.
Molecular Weight:
354.35
Purity:
99.36% (May vary between batches)
CAS Number:
[13079-95-3]
Formula:
C20H18O6
Target:
Caspase,JNK,p38 MAPK,ERK
Application Notes:
Solubility: DMSO:80 mg/mL (225.77 mM)
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