ST I4C, ST-I4C, Indole4carboxaldehyde, Indole-4-carboxaldehyde, Indole 4 carboxaldehyde
Indole-4-carboxaldehyde (ST-I4C) is a natural small molecule that mitigates methylglyoxal (MGO)-induced inflammatory responses in HepG2 cells. It functions by suppressing advanced glycation end-products (AGEs) and the expression of TNF-alpha and IFN-gamma, while modulating the NF-kappaB pathway and glyoxalase-1. This compound is a useful research tool for studying oxidative stress, inflammation, and metabolic disorders in cellular models.
Molecular Weight:
145.158
Purity:
98.89% (May vary between batches)
CAS Number:
[1074-86-8]
Formula:
C9H7NO
Target:
NF-kappaB,TNF,COX
Application Notes:
Solubility: DMSO:40 mg/mL (275.56 mM)
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