ARCC-4 is a potent VHL-recruiting PROTAC that induces low-nanomolar degradation of the androgen receptor (DC50 = 5 nM). It outperforms enzalutamide and effectively targets clinically relevant AR mutants, making it a valuable tool for prostate cancer research in both cellular and in vivo models.
Molecular Weight:
1024.18
CAS Number:
[1973403-00-7]
Formula:
C53H56F3N7O7S2
Target:
Androgen Receptor,PROTACs
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