ACE2 antibody, Clone: [MSVA-919R], Unconjugated, Rabbit, Monoclonal

Product Overview

• Article Name: ACE2 antibody, Clone: [MSVA-919R], Unconjugated, Rabbit, Monoclonal
• Biozol Catalog Number: BYT-ORB2276418
• Supplier Catalog Number: orb2276418
• Alternative Catalog Number: BYT-ORB2276418-0.5
• Manufacturer: Biorbyt
• Host: Rabbit
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant fragment (around aa705-805) of human ACE2 (exact sequence is proprietary)
• Conjugation: Unconjugated
• Alternative Names: Angiotensin I converting enzyme 2

Product Description

ACE2 antibody validated for immunohistochemistry on 76 different Normal Tissues

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MSVA-919R]
• UniProt: Q9BYF1

Application Notes

• Application Dilute: 1:100-1:200
• Application Notes: Application Notes: Positive Control: Kidney: Cells of proximal tubuli should show a moderate to strong ACE2 immunostaining with accentuation of the staining at the apical membrane. Negative Control: Kidney: Cells of distal tubuli and glomeruli should not show ACE2 immunostaining. Cellular Localization: Cytoplasmic Protocol Recommendations: Manual Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121C in pH 7.8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37C for 60 minutes. Visualization of bound antibody by the EnVision Kit (Dako, Agilent) according to the manufacturers directions

Images

Kidney Clear cell renal cell carcinoma strong strong membraous ACE2 positivity.

Kidney cortex A strong ACE2 immunostaining occurs in proximal tubuli of the kidney.

Testis Leydig cells and spermatocytes of the testis show a particularly strong ACE2 immunostaining in the testis.