Rp-Adenosine-5-O-(1-thiotriphosphate) sodium Preis auf Anfrage

Product Overview

• Article Name: Rp-Adenosine-5-O-(1-thiotriphosphate) sodium Preis auf Anfrage
• Biozol Catalog Number: BYT-ORB2276826
• Supplier Catalog Number: orb2276826
• Alternative Catalog Number: BYT-ORB2276826-50,BYT-ORB2276826-5
• Manufacturer: Biorbyt
• Category: Biochemikalien

Product Description

Rp-Adenosine-5-O-(1-thiotriphosphate) (Rp-ATP-alpha-S), a sulfur-containing nucleotide derivative isomer and a purinergic P2Y1 receptor agonist, promotes calcium mobilization in HEK293 cells expressing the human P2Y1 receptor (EC50 = 75 nM). This compound exhibits binding affinity to washed isolated human platelets (Ki = 156 nM) and attenuates ADP-induced aggregation in human platelet-rich plasma (PRP, pA2 = 4.74), as well as inhibits cAMP production triggered by prostaglandin E1 (PGE1) in human PRP (pA2 = 5.26). Furthermore, it triggers relaxation in carbamoylcholine-constricted guinea pig taenia coli strips (EC50 = 56 nM). Rp-ATP-alpha-S also contributes to the synthesis of cyclic dinucleotides, recognized by bacterial riboswitches.

Product Properties

• Molecular Weight: 611.18
• Formula: C10H12N5O12P3S.4Na
• Target: Others