8-bromo NAD+ sodium, CAS [[2022926-16-3]] Preis auf Anfrage

Product Overview

• Article Name: 8-bromo NAD+ sodium, CAS [[2022926-16-3]] Preis auf Anfrage
• Biozol Catalog Number: BYT-ORB2276832
• Supplier Catalog Number: orb2276832
• Alternative Catalog Number: BYT-ORB2276832-7400
• Manufacturer: Biorbyt
• Category: Biochemikalien

Product Description

8-Bromo NAD+ serves as a prodrug for the cyclic ADP-ribose (cADPR) inhibitor, 8-bromo cADPR, undergoing conversion to its active form by the enzyme CD38. At a concentration of 1 mM, it effectively inhibits the rise in intracellular calcium levels and chemotaxis triggered by N-formyl-Met-Leu-Phe (fMLP) in mouse bone marrow-derived neutrophils. Furthermore, when applied at 100 µM, this compound reduces LPS-induced nitrite production and decreases the secretion of TNF-alpha and IL-2 in mouse primary microglial cells.

Product Properties

• Molecular Weight: 764.3
• CAS Number: [2022926-16-3]
• Formula: C21H25BrN7O14P2.Na
• Target: Others