Ceratotoxin-1 (CcoTx1) is a peptide toxin that functions as an inhibitor of various voltage-gated sodium channel subtypes. It selectively inhibits Nav1.1/beta1, Nav1.2/beta1, Nav1.4/beta1, and Nav1.5/beta1 with IC50 values of 523 nM, 3 nM, 888 nM, and 323 nM, respectively. Additionally, Ceratotoxin-1 is known to inhibit Nav1.8/beta1.
Molecular Weight:
4044.58
Formula:
C172H256N52O50S6
Target:
Sodium Channel
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