RORgammat inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor gammat (RORgammat), with an inhibitory concentration (IC50) of 0.428 µM. It has shown efficacy in reducing Imiquimod-induced psoriasis severity in murine models.
Molecular Weight:
555.36
Formula:
C23H15Cl2F3N4O3S
Target:
ROR
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