Antitumor Agent-111 (Compound 46), a c-Met kinase inhibitor (IC50 = 46 nM), exhibits both antitumor and antiproliferative effects. It impedes the cell cycle at the G0/G1 phase and induces apoptosis.
Molecular Weight:
675.08
Formula:
C34H29ClF2N6O5
Target:
c-Met/HGFR
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