KV1.3-IN-1 (Compound trans-18) is a selective KV1.3 channel inhibitor with IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes, disrupting intracellular Ca2+ signaling and impeding T-cell activation, proliferation, and colony formation.
Molecular Weight:
430.56
Formula:
C23H30N2O4S
Target:
Potassium Channel
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