DprE1-IN-7 (Compound 64) is a DprE1 inhibitor with potent anti-tuberculosis (TB) activity, demonstrating a minimum inhibitory concentration (MIC) of 1 µM against the Mtb H37Rv strain. It exhibits antimycobacterial effects on drug-resistant strains, shows high microsomal stability, and has medium clearance.
Molecular Weight:
360.41
Formula:
C20H20N6O
Target:
Others
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