Metallo-beta-lactamase-IN-11 (compound 5f), a potent inhibitor of Metallo-beta-lactamases (MBLs), demonstrates efficacy against bacterial metallophyllactamase CphA with an IC50 value of 45 µM. At 10 µM, it inhibits NDM-1 by 49% and AIM-1 by 61%, indicating its potential for research on countering antibiotic resistance.
Molecular Weight:
453.53
Formula:
C31H23N3O
Target:
Others
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