SARS-CoV-2-IN-60 (5a) is an irreversible, SAM-competitive inhibitor of the SARS-CoV-2 nsp16-nsp10 methyltransferase with an IC50 of 9 µM. It binds a novel allosteric site, supporting its investigation as a broad-spectrum antiviral agent in coronavirus enzymatic assays and replication studies.
Molecular Weight:
335.11
Formula:
C13H7Cl2F3N2O
Target:
SARS-CoV
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