SARS-CoV-2 3CLpro-IN-19 (C5a) is a potent, non-covalent small-molecule inhibitor of the SARS-CoV-2 3CL protease, exhibiting an IC50 of 0.7 µM. It demonstrates broad-spectrum antiviral activity in vitro against Omicron subvariants, including BA.5 and XBB.1.5, with EC50 values in the nanomolar range. This compound is a valuable tool for researching coronavirus replication and developing antiviral strategies.
Molecular Weight:
451.97
Formula:
C24H22ClN3O2S
Target:
SARS-CoV
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