CDK9-IN-27 (Compound 6a), a CDK9 inhibitor with an IC50 of 0.424 µM, induces apoptosis and S-phase cell cycle arrest. It exhibits cytotoxicity against HepG2, HCT-116, and MCF-7 cell lines, with IC50 values ranging from 10.31 to 40.34 µM, rendering it applicable in cancer research.
Molecular Weight:
447.87
Formula:
C23H18ClN5O3
Target:
CDK
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