SRE-II, an amide derivative, serves as an activatable photosensitizer tailored for photodynamic cancer research, exhibiting diminished fluorescence and photosensitizing properties. Upon carboxylesterase-catalyzed amide bond cleavage, it transforms into its active form, SDU Red. In light-exposed environments, SRE-II prompts DNA damage and induces cell apoptosis, highlighting its potential as a theranostic agent for triple-negative breast cancer.
Molecular Weight:
397.59
Formula:
C15H9ClINO2
Target:
DNA/RNA Synthesis
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