GBD-9, a dual-mechanism degrader, effectively promotes the degradation of BTK and GSPT1 through recruitment of E3 ligase cereblon (CRBN). As a PROTAC molecule, GBD-9 induces BTK degradation, while also acting as a molecular glue for GSPT1 degradation, demonstrating potent inhibition of cancer cell growth.
Molecular Weight:
797.9
CAS Number:
[2864408-92-2]
Formula:
C44H47N9O6
Target:
PROTACs
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