PROTAC BCR-ABL Degrader-1 is a heterobifunctional molecule that induces targeted degradation of the Bcr-Abl oncoprotein via the ubiquitin-proteasome system. It demonstrates potent anti-proliferative activity in K562 chronic myeloid leukemia cells in vitro, making it a valuable chemical tool for investigating targeted protein degradation in oncology research.
Molecular Weight:
792.84
Formula:
C43H40N10O6
Target:
Bcr-Abl,PROTACs
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