MS15 TFA is a potent and selective PROTAC degrader of AKT isoforms, demonstrating effective degradation with IC50 values of 90 nM for AKT2, 544 nM for AKT3, and 798 nM for AKT1. This compound is a valuable chemical tool for investigating AKT signaling in cancer research and has been utilized in both cellular and in vivo studies to explore oncogenic pathways and therapeutic strategies.
Molecular Weight:
1228.47
Formula:
C66H80F3N11O7S
Target:
PROTACs,Akt
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