SJ1008030 (compound 8) TFA is a potent and selective PROTAC degrader of JAK2. It demonstrates anti-leukemic activity in vitro, inhibiting the proliferation of MHH-CALL-4 cells with an IC50 of 5.4 nM, supporting its utility in hematological cancer research.
Molecular Weight:
987.96
Formula:
C44H44F3N13O9S
Target:
JAK,PROTACs
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