PolQi2, CAS [[2565638-16-4]]

Product Overview

• Article Name: PolQi2, CAS [[2565638-16-4]]
• Biozol Catalog Number: BYT-ORB2283464
• Supplier Catalog Number: orb2283464
• Alternative Catalog Number: BYT-ORB2283464-1, BYT-ORB2283464-1, BYT-ORB2283464-10, BYT-ORB2283464-100, BYT-ORB2283464-25, BYT-ORB2283464-5, BYT-ORB2283464-50
• Manufacturer: Biorbyt
• Category: Biochemikalien

Product Description

PolQi2 is a small molecule inhibitor of DNA polymerase theta (Poltheta) that specifically suppresses its helicase activity. When combined with the DNA-PK inhibitor AZD7648, it enhances homology-directed repair (HDR) efficiency and improves the accuracy of genome editing in cellular models.

Product Properties

• Molecular Weight: 453.9
• Purity: 99.19% (May vary between batches)
• CAS Number: [2565638-16-4]
• Formula: C21H16ClN5O3S
• Target: DNA/RNA Synthesis

Application Notes

• Application Notes: Solubility: DMSO:155 mg/mL (341.48 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.27 mM)