Volanesorsen (ISIS 304801) is a chemically stabilized antisense oligonucleotide that selectively inhibits apolipoprotein CIII messenger RNA, resulting in reduced triglyceride levels and improved insulin sensitivity, Volanesorsen is actively studied as a targeted nucleic acid therapeutic strategy for hypertriglyceridemia, familial chylomicronemia syndrome, and type 2 diabetes.
Molecular Weight:
7165
CAS Number:
[915430-78-3]
Target:
Apolipoprotein
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