MMAF-OtBu is a tert-butyl ester derivative of the cytotoxic agent MMAF, designed for the synthesis of antibody-drug conjugates (ADCs). This microtubule-disrupting payload is widely used in ADC research for evaluating antitumor efficacy in both in vitro cytotoxicity assays and in vivo xenograft models.
Molecular Weight:
788.07
Purity:
98.94% (May vary between batches)
CAS Number:
[745017-95-2]
Formula:
C43H73N5O8
Target:
Microtubule Associated,ADC Cytotoxin
Application Notes:
Solubility: DMSO:40 mg/mL (50.76 mM)
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